Saya Halmat
Pharmacy Department
TIU - Erbil
Sima Mohammed
Pharmacy Department
TIU - Erbil
The Sweet Truth: Understanding the Negative Effects of Sugar
In our modern world, sugar is everywhere. From morning coffee to evening dessert, it sneaks into our diet, often without us realizing how much we consume. While a little sweetness can make life more enjoyable, too much can seriously affect our health. Let’s look at how sugar impacts various parts of our body and why it’s worth paying attention to.
Digestive System
- Disruption of gut microflora: The gut is inhabited by trillions of microorganisms that play a crucial role in nutrient absorption, immune function, and digestion. Excessive sugar intake can disrupt this balance by enhancing the growth of harmful bacteria and reducing beneficial bacteria.
- Interference with nutrient absorption: Sugar can compete with the absorption of important nutrients, such as calcium and magnesium, weakening the digestive system and overall health.
- Increased risk of digestive disorders: Excessive sugar consumption can exacerbate symptoms of irritable bowel syndrome, including bloating, diarrhea, and gas.
Immune System
Excessive sugar consumption can weaken the immune system, making you more susceptible to infections and illnesses. It impairs white blood cell function, disrupts gut microflora, disturbs hormonal balance, increases inflammation, and interferes with nutrient absorption.
Brain
- Addictive behaviors: Your brain lights up with joy every time you consume sugar due to the release of dopamine, the “feel-good” neurotransmitter. Over time, this can trigger addictive behaviors like those caused by drugs.
- Increased risk of neurodegenerative diseases: Overconsumption of sugar is linked to an increased risk of neurodegenerative diseases such as Alzheimer’s disease.
Heart
Sugar intake can adversely affect the heart mainly through these mechanisms:
- Increased blood pressure and inflammation: Excessive sugar consumption can raise blood pressure and inflammation levels.
- Higher triglyceride levels: Increased sugar intake can raise triglyceride levels, which may lead to blood clots in the arteries, increasing the risk of stroke or heart attack.
Kidneys
The kidneys filter waste from the blood and maintain electrolyte balance. Still, high sugar consumption can disrupt these functions, resulting in kidney-related issues such as an increased risk of chronic kidney disease and kidney stone formation.
Liver
The liver, the body’s detox powerhouse, struggles to process large amounts of fructose, commonly found in sweetened beverages. Excessive fructose is converted into fat in the liver, leading to non-alcoholic fatty liver disease, which can lead to inflammation, scarring, and eventually liver failure.
Skin
Cutting down on sugar can enhance skin complexion, making it look more youthful and radiant because:
- Loss of elasticity: Excessive sugar can bind to proteins and fats in the skin, causing it to lose elasticity, which leads to premature aging and wrinkles.
- Acne breakouts: High sugar intake can increase oil production and inflammation, leading to acne.
Teeth
One of the most obvious effects of excessive sugar is tooth decay. When you consume a sugary meal, the sugar molecules meet bacteria in your mouth, which thrive on sugar. The bacteria metabolize the sugar, producing an acid that attacks the tooth enamel—the hard, protective outer layer of the tooth—leading to decay.
Hormonal Imbalance
Hormones are critical for the body’s proper functioning, regulating everything from metabolism to mood. Here’s a look at how sugar consumption can disrupt these vital chemical messengers:
- Insulin: Every time you consume sugary food, your blood sugar level spikes, triggering the pancreas to release insulin to help cells absorb glucose. Repeated spikes can lead to insulin resistance, forcing the pancreas to produce more insulin, which may result in type 2 diabetes and fat storage around the abdomen, causing weight gain.
- Cortisol: Consuming high amounts of sugar can increase cortisol levels, raise stress levels, increase appetite, cause weight gain, and disrupt sleep patterns.
- Estrogen and Progesterone: Imbalances in estrogen and progesterone can lead to conditions such as polycystic ovary syndrome (PCOS) and menstrual irregularities.
- Testosterone: High sugar levels can elevate insulin and cortisol, suppressing testosterone production. Lower testosterone levels can lead to reduced muscle mass, increased body fat, and decreased overall vitality.
- Thyroid hormones: Excessive sugar can stress the adrenal glands, leading to hypothyroidism (underactive thyroid).
- Leptin and Ghrelin: Leptin signals the brain to stop eating when you are full, while ghrelin stimulates hunger. Excessive sugar can lead to leptin resistance and increased ghrelin levels, resulting in overeating, weight gain, and obesity.
Body Weight and Fat
Consuming sugary foods and beverages, which are high in calories and low in essential nutrients, can lead to excessive calorie intake without feeling full, contributing to weight gain. Additionally, sugar can spike blood sugar levels, causing increased hunger and overeating, which can progress into obesity—a major risk factor for various illnesses such as diabetes and heart disease.

